View Source

Hopkins Researchers Uncover How Antidepressants Work

Antidepressants, exercise and electroconvulsive shock therapy all work the same way to alleviate depression symptoms: by promoting stem cells in the brain to divide and create more cells. They do this by changing the activity of a “gatekeeper” gene that links stimulation in the brain to new growth, researchers at Johns Hopkins found. Variations in that gatekeeper gene cause differing responses to antidepressant drugs, suggesting that a genetic test may one day help predict which drug and dosage will work best for individual depression patients. 

Funding: The studies were supported by the National Institute of Mental Health (grant numbers MH090115 and MH087874), the National Institute of Neurological Disorders and Stroke (grant numbers NS048271, NS047344 and NS080913), the National Institute of Child Health and Human Development (grant number HD069184), the National Institute of Environmental Health Sciences (grant number ES021957), the Brain & Behavior Research Foundation, the Maryland Stem Cell Research Fund, the International Mental Health Research Organization and the Max Planck Society.

 Read More

Facebook
Twitter
View

Notes

  1. komikbookgeek reblogged this from medresearch
  2. puyo-blah reblogged this from medresearch
  3. healthandmedicineorg reblogged this from medresearch and added:
    Hopkins Researchers Uncover How Antidepressants Work Antidepressants, exercise and electroconvulsive shock therapy all...
  4. floraposteresearch reblogged this from medresearch
  5. frownedmethisface reblogged this from texasdreamer01
  6. eiluj44 reblogged this from medresearch
  7. luckysrevenge reblogged this from medresearch
  8. kyliielaine1357 reblogged this from medresearch
  9. texasdreamer01 reblogged this from medresearch
  10. syncopaticremedy reblogged this from medresearch
  11. Stacy Poliseo submitted this to medresearch